I got the remake of Secret of Mana last night. Fans of the game will know this, but I'm not very far, I've only just beaten the first boss and been exiled from Potos Village.
So far...
The game play and overall mechanics feel quite similar to the original Super Nintendo version. However, combat honestly feels easier, and I would say that's because of the game's new 3D mechanics. In the SNES version, enemy sprites always faced the camera/viewer, so they could essentially attack from all directions. In the remake, because enemies are now 3D who move and turn in a 360 degree fashion, they must be facing you to attack you, making it easily possible to get behind them, avoid being hit and deal damage yourself.
There's voice acting and cut scenes now. They feel static. Most characters' facial expressions stay exactly the same, and some of the voice acting (English) leaves a lot to be desired for, especially the main protagonist, Randi. Some of the vocals are okay, though.
The graphics don't look that good. They look pretty basic, like it came out of an iOS game or something. To be fair, that's probably the look they were going for, I imagine they didn't want to stray too far from the SNES version.
The soundtrack is so good
but some people have been complaining about it. Kotaku claims the games' "once beautiful" soundtrack has now apparently been ruined.