I suppose you could call this 'nitpicking', but I can see the occasional purple pixel on my sprite. It mostly occurs with stances where there's a hole, usually between hair and shoulders or arms and torso. The hole formed by Kyo's pants chain can also be a real problem.
That chain is also why I don't like flipping his sprite. Damn thing's asymmetrical.
I've only flipped one Kyo sprite during the 30+ comics so far, and that was in comic 9, when Links got his first dialogue. I flipped Kyo, but cut him off so as to hide the asymmetrical pants chain.