While I love both Harold and Kumars, their background really didn't connect with how I view stoner culture. These are two above intelligent guys who just happen to have the worst of luck. While I consider myself an above intelligent stoner as well, my friends and I have had more wacky adventures just in two apartments than we have ever on road trips.
Cheech and Chong started a revolution, but they are from an older generation. Some of their humor is still dead on, but other times I just can't relate with them.
Jay and Silent Bob and two slacker stoners who constantly quote star wars and comic books, originally never left their home territory of New Jersey, and had a blast with whatever it was they had at hand. I could relate with these guys.
Although now I look back on it, the duo I most relate with are the two main characters from Grandma's Boy. Both stoners who spent most of their time playing video games and hanging out with crazy people in a random living room.